Safety Database Selection And Implementation Services

Empowering Global Pharmacovigilance Through Reliable, Compliant, And Scalable Safety Systems.

Selecting and implementing the right safety database is one of the most critical decisions for any pharmacovigilance operation. The system must capture, manage, and report safety data across global markets with accuracy, consistency, and full regulatory alignment. A poor database decision or an unvalidated implementation can lead to inefficiencies, compliance risks, and costly inspection findings.

Fidelity Health Services (FHS) provides comprehensive Safety Database Selection and Implementation Services designed to help life-sciences organizations establish robust, validated, and future-ready safety systems.
Our expertise spans from technology evaluation to post-deployment optimization, ensuring every implementation aligns with both business objectives and global pharmacovigilance requirements.

Why Safety Database Selection Matters

Pharmaceutical and biotech companies operate in a dynamic environment where global regulatory authorities continuously evolve data submission and reporting requirements. The chosen database must adapt to new standards while maintaining high performance and data integrity.

Key industry challenges include:

  • Managing large volumes of ICSRs across multiple therapeutic areas and regions
  • Integrating data from clinical, post-marketing, and medical information sources
  • Ensuring compliance with ICH E2B(R3), FDA, EMA, and MHRA guidelines
  • Supporting multi-affiliate operations with real-time visibility and audit trails

Fidelity addresses these challenges by combining domain expertise, system knowledge, and regulatory insight to deliver safety databases that are compliant, efficient, and scalable.

Our Core Capabilities

1. System Evaluation and Selection

Fidelity's consultants perform a structured assessment to identify the safety database that best aligns with organizational requirements, size, and regulatory obligations.

Core Competencies
  • Comparative evaluation of platforms such as Argus, ArisG, Veeva, and custom systems
  • Functional and technical requirement mapping aligned with GVP modules
  • Cost, scalability, and integration feasibility analysis
  • Vendor qualification and validation documentation review

Our systematic evaluation framework ensures clients invest in the right technology for long-term sustainability and compliance confidence.

2. System Implementation and Configuration

Once the appropriate platform is selected, FHS executes a full-cycle implementation using a standardized and validated approach.

Implementation Coverage
  • Requirement analysis and configuration blueprint development
  • Case intake, follow-up, and submission workflow setup
  • Data model customization for products, events, and reporting workflows
  • Integration with gateways, call centers, and document management systems

Each implementation is carried out under controlled change management with full traceability from design to deployment.

3. Validation and Verification

Validation is a regulatory imperative for all GxP systems. Fidelity's Computer System Validation (CSV) and Computer Software Assurance (CSA) teams ensure every database implementation is inspection-ready.

Validation Deliverables
  • Validation master plan, IQ, OQ, and PQ protocols
  • Traceability matrices linking requirements to executed tests
  • Controlled testing, deviation handling, and summary reporting
  • Performance verification to ensure system stability under operational load

All validation activities align with 21 CFR Part 11, EU Annex 11, and GAMP5 standards, ensuring audit confidence.

4. Integration with Pharmacovigilance Ecosystems

Modern drug safety operations demand seamless data flow across systems. Fidelity enables integration between safety databases and key platforms across the regulatory landscape.

Integration Capabilities
  • Connection with E2B gateways for global authority submissions
  • Interface with medical information and quality management systems
  • Data exchange with signal detection and analytics platforms
  • Secure API-based interoperability for third-party tools and affiliates

These integrations eliminate data silos and enable a unified, transparent safety ecosystem.

5. Integration with Pharmacovigilance Ecosystems

Implementation success depends on how effectively end-users adopt the system. Fidelity provides comprehensive training and hypercare support to ensure operational continuity.

Support Highlights
  • Role-based user training and knowledge transfer
  • Operational SOP development and process documentation
  • Hypercare support during the stabilization phase
  • Ongoing system maintenance, upgrades, and revalidation services

Our support model ensures that clients gain maximum operational value from their investment.

The Fidelity edge

Fidelity Health Services combines regulatory expertise, technical mastery, and operational experience to deliver safety database implementations that stand out for precision and reliability.

    Distinct Advantages
  • Proven success across global pharma and biotech organizations
  • Certified implementation specialists for Argus, ArisG, and other leading systems
  • Proprietary accelerators reducing deployment and validation timelines
  • Scalable design adaptable to evolving business and regulatory needs
  • End-to-end accountability from system selection to post-go-live support
  • Our focus is not only on technology enablement but also on delivering systems that enhance pharmacovigilance efficiency and compliance assurance.

Quality and Governance Assurance

Every implementation is governed by Fidelity's Quality Management System (QMS) and validation governance framework.

  • Alignment with ICH, FDA, EMA, and MHRA data integrity standards
  • Documentation control ensuring traceability across all phases
  • Internal quality audits and CAPA processes for continuous improvement
  • Secure hosting and data protection in compliance with HIPAA and GDPR

Your Next Step

A reliable safety database is the foundation of every pharmacovigilance operation. Partner with Fidelity Health Services to implement validated, scalable, and regulator-trusted safety systems tailored to your organization's global needs.

Talk to our Safety System Implementation Experts Today

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