Data Validation Services

Turning Raw Data Into Reliable, Compliant, & Inspection-Ready Evidence.

Every safety decision depends on data you can defend. From ICSR intake to E2B transmission and aggregate reporting, the integrity of each field, mapping, and transformation determines regulatory trust. Fidelity Health Services (FHS) delivers comprehensive Data Validation that safeguards accuracy, traceability, and compliance across your pharmacovigilance ecosystem-while embedding system-level assurance so validated data always sits on validated systems.

Why it matters

Safety data flows through multiple sources, databases, gateways, and reports. Without rigorous controls, issues surface late-often during inspections-creating avoidable findings, delays, and risk. FHS addresses common gaps like mismatched case data, inconsistent coding, migration defects, and malformed submissions through a structured, audit-ready validation framework.

At the same time, regulators expect proof that the computerized systems supporting these data flows perform as intended. Our approach aligns with 21 CFR Part 11, EU Annex 11, GAMP5, and current FDA Computer Software Assurance (CSA) thinking to ensure your data sits inside a controlled, validated environment.

What we validate

1. End-to-End Safety Data

  • ICSR data within Argus, ArisG, and custom PV solutions
  • Cross-checks between intake sources, migration outputs, and reporting layers
  • Conformance for E2B R2/R3 content, structure, and acknowledgments
  • Automated detection of missing, invalid, or inconsistent elements
  • All evidence is organized for rapid retrieval during internal and external audits.

2. Migrations and Integrations

  • Source-to-target reconciliations with field-level mapping verification
  • Transformation logic checks and record-level comparisons
  • Parallel runs with tracked deviations and defect resolution
  • The result is functionally equivalent, loss-free operation post-cutover.

3. Regulatory Submissions

  • XML schema and gateway configuration checks
  • Content validation for codes, narratives, and transmission integrity
  • Full traceability from source database to submission package
  • We confirm both technical acceptance and regulatory expectations.

4. Periodic and Aggregate Reports

  • Validation of extraction queries and aggregation logic
  • Cross-verification of counts, frequencies, and outcomes
  • QC of DSUR, PSUR, and PBRER data tables and narratives
  • All checks are documented to withstand inspections.

The system layer
behind your data

While the page focuses on Data Validation, we embed essential Computer/System Validation so your data controls are never undermined by the platform. Our Validation Center of Excellence plans and executes risk-based validation for PV systems, upgrades, migrations, and analytics environments, using IQ/OQ/PQ where appropriate and CSA to prioritize what truly impacts patient safety and product quality.

System Scope Includes

  • Safety databases and PV platforms
  • E2B gateways, integration pipelines, and reporting tools
  • BI dashboards used for regulatory analytics
  • We keep documentation inspection-ready and aligned to your QMS.

How we work

Risk-Based Strategy & Planning

We establish a clear validation roadmap with scope, deliverables, test matrices, and traceability. This ensures efficiency, auditability, and alignment with your procedures.

Execution With Evidence

We combine automated rules, scheduled checks, and targeted manual review to maximize coverage while reducing cycle time. Exception workflows drive timely remediation, and every activity is version-controlled with electronic signature traceability.

Continuous Monitoring & Lifecycle Control

Validation continues after go-live. Periodic reviews, change control, access checks, and audit-trail verification maintain a consistent state of control across releases and patches.

Quality and governance

All Data Validation operates under FHS's Quality Management System and data-integrity governance, aligned to FDA, EMA, PMDA, and MHRA expectations, with CAPA-driven improvement, secure handling, and documentation suitable for global inspections.

In parallel, our Computer/System Validation governance applies 21 CFR Part 11, EU Annex 11, and GAMP5 with standardized templates and internal audits that keep records inspection-ready.

The Fidelity edge

  • Regulatory-grade documentation with end-to-end traceability
  • Multi-system PV expertise across Argus, ArisG, and custom solutions
  • CSA-driven focus on risk, speed, and critical functionality
  • Validation accelerators that compress timelines without compromising control
  • Seamless support from planning through audit response
  • These advantages convert complex data streams into defensible regulatory evidence-on platforms that regulators trust.

Talk to our
Data Validation Experts

Validated data on validated systems is the foundation of credible pharmacovigilance. Let's design a validation program that fits your portfolio, timelines, and inspection profile.

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